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LSI e-Catalogue 2012 Veterinary Diagnostic Kits Elisa, PCR and BVD (English) |
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e-Catalogue LSI 2012 des kits de diagnostic vétérinaire Elisa, PCR et BVD (FR) |
West Nile virus (WNV) is a flavivirus transmitted by mosquitoes. This virus can cause fatal neurological diseases in humans and horses (in about 1% of infections). Birds are the main reservoir hosts of the virus. The monitoring of this virus by health authorities has helped to highlight an increase in severe forms of the disease in the late 90’s. Indeed, several human epidemics occurred in Europe, North America and around the Mediterranean basin. Also, several epidemics affecting only horses have been described in Europe since 1998.
West Nile virus presents a significant variability of its nucleotidic sequence: lineage 1 is responsible for the vast majority of recent outbreaks and epidemics, while lineage 2 was responsible for the epidemics and equine epizootics in Hungary in 2008. Therefore, it is necessary to develop adapted molecular tools to efficiently amplify the diverse strains of West Nile virus circulating in Europe, especially pathogenic lineage 1 and 2 strains.