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LSI e-Catalogue 2012 Veterinary Diagnostic Kits Elisa, PCR and BVD (English) |
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e-Catalogue LSI 2012 des kits de diagnostic vétérinaire Elisa, PCR et BVD (FR) |
Lawsonia intracellularis is an obligate intracellular Gram negative bacillus that is the infectious agent of proliferative enteritis (PE). PE corresponds to a set of disorders characterised by thickening of the mucosa of the small intestine (and sometimes the large intestine) due to proliferation of gut epithelial cells. The resultant epithelium is immature with no goblet cells and sometimes shows traumatic mucosal damage. The condition is most common in pigs but it can also affect horses, dogs and rabbits. In pigs, PE tends to strike animals of between 6 and 20 weeks of age but it can also affect younger animals or animals of several years of age. PE is usually chronic, causing grey diarrhoea and retarded growth. Acute forms are sometimes seen, with gastrointestinal bleeding (soft, black stools) followed by death. PE is found in pigs all over the world and has major economic impact.